July 1, 2014
With modern automated equipment for immunoblotting and the use of modern linear blots of German company Euroimmune, Biokurs significantly enhances the capabilities of a modern clinician in the diagnosis of an autoimmune disease. One blot allows simultaneous determination from 2-3 to 15-18 different autoantibodies that significantly reduces the cost of inspection and provides information in more details.
The use of fluorescent microscopy is the gold standard for detection of autoantibodies. We have modern fluorescent microscope and special tissue sections produced by German company Euroimmune, which enable both screening and precision determination of any autoantibodies according to the order of doctor-clinician.
LIST OF DIAGNOSTIC POSSIBILITIES OF AUTOIMMUNE DISEASES OFFERED BY BIOKURS
|
Test name |
Аntigens |
Diseases |
|
ANA-profile -15 Ag |
ds-DNA, RNP/sm, Sm, nucleosomes, hystones, ss-DNA, SS-A, SS-В, Scl-70, PM-Scl, Jo-1, CENP-B, RNP, АМА-М2, PCNA |
SLE, Drug induced SLE, Sjorgen"s syndrome, neonatal SLE, SSD, PM/DM , SSD/CREST syndrome, PBC, SLE accompanied with nephritis and interscitial pneumoni or polyneuritis |
|
Liver profile-4 Ag |
AMA-M-2 SLA/LP , LKM, LC-1 LKM |
PBC, autoimmune hepatitis, hepatitis C ,autoimmune pancreatitis, autoimmune nephritis |
|
Systemic sclerosis profile-13 |
Scl-70, CENP-A, CENP-B, RNA-polymerase 3-11kD and 155kD, NOR90,Th/To, PM-Scl-100 аnd 75, Ro-52, PDGFR, fibrillarin, Ku |
SSD, PM, Sjorgen"s syndrome, CREST syndro, SLE, MCTD |
|
Vasculitis profile-3 |
MPO (pANCA), PR3 (cANCA), GMB |
Systemical vasculitis - viral (CMV, HIV, hepatitis В , С) and drug induced . RA, polyneuritis, periarteriitis nodosum, Shenlain-Genoch"s purpura, cryoglobullinemia, paraneoplastic syndrome, Wegener"s syndrom, Goodpaster"s syndrome, Charg-Shtraus" syndrome, autoimmune glomerulonephritis, primary sclerotic holangitis, ulcerating collitis |
|
Myositis profile-7 |
Mi-2,Ku,PM- Scl, Jo-1, PL-7, PL-1, Ro-52 |
PM, DM , overlap syndrome |
|
Gangliosides profile-3 |
GM-1, GD1B, GQ1b |
Demielinizating illness of neuronal fibres – Gien-Barres" syndrome, neuropathia e.c. |
|
Neuronal profile-7 |
amphyphysin,СV2.1,PNMA2,Ri,Jo,Hu |
Paraneoplastic neuropathy connected with lung, bronch, breast or ovary cancers, Chodjkin"s lymphomа - ataxya, encephalomielitises, chorea, rigidity |
|
ANA/ANCA IFA |
Ab to nuclear antigens (IFA screening) |
Screening test for detection autoimmune diseases - detects appr. 150 different type autoantibodies |
|
Anti-MCV |
Ab to modifide citrulated vinmentin |
RA |
|
Anti-CCP |
Ab to cyclic citrulated peptide |
RA |
|
RF |
Ab to Ga-epitope of Fc-fragment IgG |
RAandmanyotherAID |
|
АСА IgG , IgM |
Аb to cardyolipin |
Phospholipid syndrom |
|
АРА IgG , IgM |
Ab to phospholipids |
Phospholipid syndrom |
|
Аnti-TG |
Аb to thyreoglobulin |
Autoimmune thyreoiditis (Choshimoto, Greivs diseases) |
|
Аnti-ТРО |
Аb to thyreoperoxidase |
Autoimmune thyreoiditis (Choshimoto, Greivs diseases) |
|
Anti-Gliadin IgA , IgG |
Ab to gliadin |
Celiacia, gluten intolerancy |
|
Anti-tsTG IgA |
Ab to tissure specific transglutaminase |
Celiacia, gluten intolerancy |